MOTS-C 10mg

MOTS‑c 10 mg (Mitochondrial‑Derived Peptide)

Overview
MOTS‑c is a 16‑amino‑acid peptide encoded by mitochondrial DNA (an open reading frame within the 12S rRNA), recognized for its bioactive "mitokine" properties It plays a key role in cellular energy regulation and systemic metabolism through activation of AMPK pathways.

Mechanism of Action

• AMPK activation & metabolic flexibility: Enhances glucose uptake in skeletal muscle (even independent of insulin), boosts fatty‑acid β‑oxidation, and supports the "browning" of white fat 

• Nuclear translocation: Under metabolic stress, MOTS‑c enters the nucleus to modulate genes involved in mitochondrial biogenesis and antioxidant response 

Potential Benefits (Based on Preclinical Research)

• Improved exercise capacity: Treatment doubled running duration and distance in aged and obese mice 

• Enhanced insulin sensitivity & metabolic health: Research in mice shows improved glucose control, reduced fat mass, prevention of diet‑induced obesity, and better metabolic profiles 

• Supports healthy aging & longevity: Linked to maintaining metabolic balance, preserving muscle function, bone health (via TGF‑β/Smad), cardiovascular protection, and possibly extending lifespan in animal models 

• Postmenopausal metabolic protection: May reduce fat accumulation and enhance brown-fat activity in estrogen‑deficient models .

Chemical & Physical Properties

• Sequence: Met‑Arg‑Trp‑Gln‑Glu‑Met‑Gly‑Tyr‑Ile‑Phe‑Tyr‑Pro‑Arg‑Lys‑Leu‑Arg 

• Formula: C₁₀₁H₁₅₂N₂₈O₂₂S₂ Molecular weight: ~2174.6 Da 

• Purity: ≥ 99%, supplied as lyophilized powder.

• Stability & Storage: Stable in powder form; dissolved aliquots are stable ~3 weeks at +4 °C and ~3–4 months at –20 °C; avoid repeated freeze‑thaw 

Intended Use & Research Context

Research Use Only Disclaimer

All products sold by HappyPeps are intended for laboratory research purposes only and are not for human consumption. Our peptides and compounds are not approved by the FDA for diagnostic, therapeutic, or clinical use. They are strictly intended for qualified researchers and institutions engaged in in vitro or preclinical research and experimentation.

By purchasing from HappyPeps, you agree to the following:

• You are a licensed researcher, laboratory, or institution with appropriate knowledge and qualifications to handle chemical and biological research materials.

• You will not use any product for medical, veterinary, or household use, or in humans or animals.

• You understand that these materials may present hazards and require safe handling, storage, and disposal in accordance with regulatory standards.

• You accept full responsibility for compliance with local, state, and federal laws governing the use of research chemicals and peptides.

HappyPeps assumes no liability for misuse, mishandling, or any consequences arising from the use of its products. All buyers must be 18 years or older.

Use at your own risk. For research purposes only.